Vyvanse

What is Vyvanse?

Vyvanse, or lisdexamfetamine, is a modified form of amphetamine. It’s designed as a prodrug, meaning it is inactive until your body processes it. Once ingested, it’s converted into dextroamphetamine, the active ingredient that helps manage ADHD symptoms.

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Advantages of Vyvanse Over Adderall:

Vyvanse has several benefits compared to other ADHD medications like Adderall:

1. Smoother, Longer-Lasting Effect: Vyvanse provides a more gradual and extended release of the active medication. While Adderall XR typically lasts 8-10 hours, Vyvanse offers about 2 extra hours of symptom control. This extended duration can lead to a smoother transition as the medication wears off, with many patients reporting a less abrupt "crash" at the end of the day.

2. Reduced Abuse Potential: Because Vyvanse takes longer to take effect, the risk of abuse is lower compared to Adderall.

   
   

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Who Can Take Vyvanse?

Vyvanse is FDA-approved for:

• ADHD: For patients aged six and older.

• Binge Eating Disorder: To help control compulsive overeating.

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It’s also sometimes prescribed off-label for conditions like narcolepsy and treatment-resistant depression.

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How Long Does Vyvanse Last?

Vyvanse typically provides relief for 10-12 hours. It’s best taken in the morning with or after breakfast to avoid excessive weight loss, as it can suppress appetite.

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How Does Vyvanse Work?

As a prodrug, Vyvanse remains inactive until it’s absorbed in the digestive system, where it’s converted into dextroamphetamine and l-lysine. Dextroamphetamine then works by enhancing the activity of the neurotransmitters norepinephrine and dopamine. This increase in neurotransmitter activity in different parts of the brain helps:

• Improve Attention and Focus: By boosting dopamine and norepinephrine in areas like the dorsolateral prefrontal cortex.

• Reduce Hyperactivity: By enhancing dopamine activity in the basal ganglia.

• Manage Depression and Fatigue: By modulating neurotransmitter levels in the medial prefrontal cortex and hypothalamus.

  
  

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What’s the Recommended Dose of Vyvanse?

Dosage varies based on age and response to the medication:

• Children and Teens: Start with 10-20 mg, gradually increasing as needed. The manufacturer suggests a starting dose of 30 mg, but adjustments are often made based on the initial response.

• Adults: Starting doses can range from 10 to 30 mg, with adjustments based on individual needs or previous use of similar medications.

  
  

Your healthcare provider will tailor a dosing plan that best suits your needs.

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Can Vyvanse Capsules Be Opened?

Yes, Vyvanse capsules can be opened and mixed with soft foods like applesauce or yogurt, or even dissolved in orange juice or water.

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What Are the Major Side Effects of Vyvanse and Other Stimulants?

Stimulants, including Vyvanse, are commonly prescribed for ADHD due to their high effectiveness and general tolerability. However, there are side effects to monitor, particularly:

1. Appetite Suppression: Leading to weight loss, particularly in children.

2. Insomnia: More likely if the medication is taken too late in the day.

3. Tics: Both motor and verbal tics can occur, especially in young boys.

   
   

Other Possible Side Effects:

• Gastrointestinal Upset: Nausea, stomach pain, or diarrhea.

• Headache: A common side effect when starting or adjusting the dose.

• Dry Mouth: A frequent complaint that can often be managed with increased water intake.

  
  

Vyvanse offers a reliable option for managing ADHD symptoms, with distinct advantages in terms of duration and potential side effects. As with any medication, it’s essential to work with your healthcare provider to find the right dosage and monitor for any adverse effects.

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Written by:

Joeseph Gagnon Jr.