Tebonin (ginko biloba extract) for Tardive Dyskinesia (also found to help tinnitus, vertigo, and symptoms of dementia)
- Kevin Keane
- Aug 13, 2024
- 2 min read
Updated: Sep 16, 2024
Tebonin is a ginkgo extract with the generic name EGb 761 that has evidence in tardive dyskinesia (also found to help with tinnitus, vertigo, cognitive decline, and symptoms of dementia). The American Academy of Neurology included tebonin in its list of 4 standard treatments for tardive dyskinesia.
Tardive dyskinesia is one of the major side effects of long-term neuroleptic (antipsychotic) treatment. Increased reactive oxygen species and oxidative stress has been proposed as possible etiopathologic mechanisms. This can look like involuntary movements of the face, jaw, tongue, or even the body. Your provider at Philadelphia Integrative Psychiatry can help assess this during one of your in person sessions.
Here is some background information on this supplement: Tebonin came out in 1965 and has mainly been used for dementia and age related cognitive decline. Tebonin helps maintain blood circulation to the peripheral areas of the body such as legs feet and hands as well as maintain capillary health and cognitive function.
It has neuroprotective effects and antioxidant effects that suggested it may treat tardive dyskinesia, and was tested in 3 randomized controlled trials totaling 300 patients where it worked with a very small p-value: 4 zeros. By comparison our FDA approved medications (Ingrezza and Austedo) were tested in about 400 patients each, and arrived at a p-value that is 100-times SMALLER than tebonin’s: only 2 zeros!!!
Where to get Tebonin:
This is the brand I recommend as it is made in Germany and is approved by their regulators as an actual prescription medication over there (here it is over the counter).
Dosing:
Recommended dosing for tebonin: Take 1 tebonin 120mg tablet Daily. Tebonin tablets should be taken independent of meals.
Here is some research backing it up:
Written by:
Joseph Gagnon Jr.